Ligand id: 2182

Name: desmopressin

Structure and Physico-chemical Properties

2D Structure
No information available.
Summary of Clinical Use
Desmopressin has long been used to treat bed-wetting, central cranial diabetes insipidus, and increased thirst and urination caused by head surgery or head trauma. In March 2017, the US FDA approved desmopressin acetate in a nasal spray formulation as the first treatment for nocturia due to nocturnal polyuria. A tablet formulation suitable for sublingual administration was FDA approved for this latter indication in June 2018.
Mechanism Of Action and Pharmacodynamic Effects
Desmopressin acetate works in nocturnal polyuria by increasing the absorption of water through the kidneys, which leads to less urine production.