desmopressin

Ligand id: 2182

Name: desmopressin

Structure and Physico-chemical Properties

2D Structure
References
1. Cheng LL, Stoev S, Manning M, Derick S, Pena A, Mimoun MB, Guillon G. (2004)
Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4.
J Med Chem47: 2375-2388. [PMID:15084136]
2. Chini B, Mouillac B, Ala Y, Balestre MN, Trumpp-Kallmeyer S, Hoflack J, Elands J, Hibert M, Manning M, Jard S et al.. (1995)
Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.
EMBO J.14 (10): 2176-82. [PMID:7774575]
3. Cotte N, Balestre MN, Phalipou S, Hibert M, Manning M, Barberis C, Mouillac B. (1998)
Identification of residues responsible for the selective binding of peptide antagonists and agonists in the V2 vasopressin receptor.
J Biol Chem273: 29462-29468. [PMID:9792651]
4. Jasper JR, Harrell CM, O'Brien JA, Pettibone DJ. (1995)
Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells.
Life Sci57: 2253-2261. [PMID:7475979]
5. Nakamura S, Yamamura Y, Itoh S, Hirano T, Tsujimae K, Aoyama M, Kondo K, Ogawa H, Shinohara T, Kan K, Tanada Y, Teramoto S, Sumida T, Nakayama S, Sekiguchi K, Kambe T, Tsujimoto G, Mori T, Tominaga M. (2000)
Characterization of a novel nonpeptide vasopressin V(2)-agonist, OPC-51803, in cells transfected human vasopressin receptor subtypes.
Br J Pharmacol129: 1700-1706. [PMID:10780976]
6. Phalipou S, Cotte N, Carnazzi E, Seyer R, Mahe E, Jard S, Barberis C. (1997)
Mapping peptide binding domains of the human V1a vasopressin receptor with a photoactivatable linear peptide antagonist.
J Biol Chem272: 26536-26544. [PMID:9334232]
7. Saito M, Tahara A, Sugimoto T. (1997)
1-desamino-8-D-arginine vasopressin (DDAVP) as an agonist on V1b vasopressin receptor.
Biochem Pharmacol53: 1711-1717. [PMID:9264324]
8. Serradeil-Le Gal C, Raufaste D, Double-Cazanave E, Guillon G, Garcia C, Pascal M, Maffrand JP. (2000)
Binding properties of a selective tritiated vasopressin V2 receptor antagonist, [H]-SR 121463.
Kidney Int58: 1613-1622. [PMID:11012895]
9. Tahara A, Saito M, Sugimoto J, Tomura Y, Wada KI, Kusayama T, Tsukada J, Ishii I, Yatsu T, Uchida W, Tanaka A. (1998)
Pharmacological characterization of the human vasopressin receptor subtypes stably expressed in chinese hamster ovary cells.
Br J Pharmacol125: 1463-1470. [PMID:9884074]
10. Thibonnier M, Preston JA, Dulin N, Wilkins PL, Berti-Matera LN, Mattera R. (1997)
The human V3 pituitary vasopressin receptor: ligand binding profile and density-dependent signaling pathways.
Endocrinology.138: 4109-4122. [PMID:9322919]