clotrimazole

Ligand id: 2330

Name: clotrimazole

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 17.82
Molecular weight 344.11
XLogP 8.56
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used for the local treatment of fungal and yeast infections of the skin such as ringworm, athlete's foot and jock itch, in additional to the treatment of vaginal yeast infections.
Mechanism Of Action and Pharmacodynamic Effects
The primary mechanism of action of clotrimazole is the inhibition of fungal growth via the disruption of cell walls.