Ligand id: 3370

Name: chlordiazepoxide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 50.46
Molecular weight 299.08
XLogP 3.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat anxiety disorders, muscle spasm and symptoms of acute alcohol withdrawl.
Mechanism Of Action and Pharmacodynamic Effects
Chlordiazepoxide binds to the benzodiazepine (BZD) binding sites on GABAA receptor/ion channel complexes in the central nervous system. This acts to increase binding of inhibitory GABA at these sites and results in overall neuro-inhibition, observed as the sedative, hypnotic, anxiolytic and muscle relaxant actions of the drug.
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