Ligand id: 3370

Name: chlordiazepoxide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 50.46
Molecular weight 299.08
XLogP 3.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Drummond AH, Hughes PJ, Ruiz-Larrea F, Joels LA. (1989)
Use of receptor antagonist in elucidating the mechanism of action of TRH in GH3 cells.
Ann. N. Y. Acad. Sci., 553: 197-204. [PMID:2566295]
2. Straub RE, Frech GC, Joho RH, Gershengorn MC. (1990)
Expression cloning of a cDNA encoding the mouse pituitary thyrotropin-releasing hormone receptor.
Proc Natl Acad Sci U S A, 87: 9514-9518. [PMID:2175902]