flunitrazepam

Ligand id: 4193

Name: flunitrazepam

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 75.81
Molecular weight 313.09
XLogP 3.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Flunitrazepam may be used to treat some cases of severe insomnia.
Mechanism Of Action and Pharmacodynamic Effects
Flunitrazepam binds nonspecifically to the benzodiazepine recognition site of GABAA chloride channels and allosterically potentiates GABA-ergic neuro-inhibition..