Ligand id: 4840

Name: sulfasalazine

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View more information in the IUPHAR Pharmacology Education Project: sulfasalazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 149.69
Molecular weight 398.07
XLogP 4.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of rheumatoid arthritis and inflammatory bowel disease
Mechanism Of Action and Pharmacodynamic Effects
The exact mechanism of action of sulfasalazine is unknown. For an overview on its established actions please see the DrugBank link on the Summary tab of this ligand page.
External links