Ligand id: 589

Name: irbesartan

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View more information in the IUPHAR Pharmacology Education Project: irbesartan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 87.13
Molecular weight 428.23
XLogP 7.21
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of hypertension and diabetic nephropathy.
Mechanism Of Action and Pharmacodynamic Effects
For a complete overview of the mechanism of action of irbesartan, please use the DrugBank link on this ligand page.