camostat

Ligand id: 6432

Name: camostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 137.31
Molecular weight 398.16
XLogP 2.41
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Spectrum of indications in the literature including pancreatitis. This drug appears to have marketing approval only in Japan and South Korea. More recent clnical indications include cystic fibrosis since prostasin is a channel-activating protease for the regulation of epithelial sodium absorption [1] .
Mechanism Of Action and Pharmacodynamic Effects
Serine protease inhibitor.