Ligand id: 6586

Name: tirofiban

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: tirofiban

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 14
Topological polar surface area 113.11
Molecular weight 440.23
XLogP 4.01
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in combination with heperin to treat acute coronary syndrome.
Mechanism Of Action and Pharmacodynamic Effects
Reversible antagonist of fibrinogen binding to integrin receptor αIIbβ3 resulting in inhibition of platelet aggregation.
External links