Ligand id: 6826

Name: levetiracetam

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 63.4
Molecular weight 170.11
XLogP -0.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
An anticonvulsant medication used to treat epilepsy
Mechanism Of Action and Pharmacodynamic Effects
Blocks voltage-gated N-type calcium channel α1B subunit (CACNA1B), which is believed to prevent hypersynchronization of epileptiform burst firing associated with seizures. May also modulate vesicle exocytosis by interacting with synaptic vesicle glycoprotein 2A (SV2A).
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