levetiracetam

Ligand id: 6826

Name: levetiracetam

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 63.4
Molecular weight 170.11
XLogP -0.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Kenda BM, Matagne AC, Talaga PE, Pasau PM, Differding E, Lallemand BI, Frycia AM, Moureau FG, Klitgaard HV, Gillard MR et al.. (2004)
Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity.
J. Med. Chem.47 (3): 530-49. [PMID:14736235]
2. Noyer M, Gillard M, Matagne A, Hénichart JP, Wülfert E. (1995)
The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes.
Eur. J. Pharmacol.286 (2): 137-46. [PMID:8605950]