Ligand id: 6850

Name: trilostane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 76.78
Molecular weight 329.2
XLogP 2.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Was used to treat Cushing's syndrome, but was withdrawn from the US market in 1994
Mechanism Of Action and Pharmacodynamic Effects
Inhibits 3-β-hydroxysteroid dehydrogenase 2 (HSD3B2).