Ligand id: 7216

Name: loratadine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 42.43
Molecular weight 382.14
XLogP 4.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Loratidine is used to relieve the symptoms of allergic rhinitis and chronic idiopathic urticaria.
Mechanism Of Action and Pharmacodynamic Effects
Loratadine blocks the action of endogenous histamine at the histamine H1 receptor.
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