loratadine

Ligand id: 7216

Name: loratadine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 42.43
Molecular weight 382.14
XLogP 4.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1993))
IUPAC Name
ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate
International Nonproprietary Names
INN number INN
5864 loratadine
Synonyms
Claritin® | SCH-29851
Database Links
CAS Registry No. 79794-75-5
ChEMBL Ligand CHEMBL998
DrugBank Ligand DB00455
GtoPdb PubChem SID 178103791
PubChem CID 3957
Search Google for chemical match using the InChIKey JCCNYMKQOSZNPW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JCCNYMKQOSZNPW
Search PubMed clinical trials loratadine
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Search UniChem for chemical match using the InChIKey JCCNYMKQOSZNPW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JCCNYMKQOSZNPW
Wikipedia Loratidine
Comments
Loratidine is an antihistamine; peripheral H1 receptor antagonist; antiallergic agent.