Ligand id: 7277

Name: probucol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 91.06
Molecular weight 516.31
XLogP 11.57
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to reduce circulating cholesterol levels.
Mechanism Of Action and Pharmacodynamic Effects
This drug inhibits the ATP-binding cassette transporter, ABCA1, which is involved in cellular lipid efflux [1,3]. Additional molecular mechanisms of action have been suggested. See the DrugBank link for further details.