probucol

Ligand id: 7277

Name: probucol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 91.06
Molecular weight 516.31
XLogP 11.57
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1977))
Withdrawn drug? Yes
IUPAC Name
2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol
International Nonproprietary Names
INN number INN
2928 probucol
Synonyms
DH-581 | Lorelco®
Database Links
CAS Registry No. 23288-49-5
ChEMBL Ligand CHEMBL608
DrugBank Ligand DB01599
GtoPdb PubChem SID 178103851
PubChem CID 4912
Search Google for chemical match using the InChIKey FYPMFJGVHOHGLL-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey FYPMFJGVHOHGLL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FYPMFJGVHOHGLL
Wikipedia Probucol
Comments
Probucol is a lipid-lowering drug. Marketing of this drug was ceased in 1995 in the US due to safety concerns.