ABT-384

Ligand id: 7357

Name: ABT-384

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 91.56
Molecular weight 493.27
XLogP 2.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
When tested at doses associated with complete brain HSD-1 inhibition, ABT-384 did not produce symptomatic improvement in AD [3].