albiglutide

Ligand id: 7386

Name: albiglutide

No information available.
Summary of Clinical Use
Albiglutide is approved to treat type 2 diabetes mellitus in conjunction with diet and excercise.
Mechanism Of Action and Pharmacodynamic Effects
Albiglutide mimics the effects of endogenous GLP-1 on insulin secretion from pancreatic β-cells, reduction of food intake and induction of satiety at the central nervous system level. Due to it's extended half-life, meaning it only has to be injected once per week, this drug should be more patient friendly than the current GLP-1 analogs that require once or twice daily injections. Although this drug binds to the GLP1R, we have been unable to find affinity data for this drug at the human GLP1R to substantiate its MMOA. Therefore we have not tagged a primary target for this drug.
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