Ligand id: 7386

Name: albiglutide

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Bioactivity Comments
In a study investigating the pharmacodynamics, pharmacokinetics, safety and tolerability of albiglutide, the drug was reported to improve fasting plasma glucose and postprandial glucose in type 2 diabetes patients [4]. The only affinity data for this compound (called albugon in the article) was generated using cells expressing the rat GLP-1 receptor, where the EC50 was reported as 20nM [1].
Selectivity at rat GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
GLP-1 receptor Agonist Agonist 7.7 pEC50 - 1
pEC50 7.7 (EC50 2x10-8 M) [1]