Ligand id: 7697

Name: AZD0328

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 25.36
Molecular weight 216.13
XLogP 1.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Mechanism Of Action and Pharmacodynamic Effects
AZD0328 modulation of α7 nAChRs enhances cortical dopamine levels and this may be causative in the positive behavioral responses reported in animal models treated with this compound [2].