Ligand id: 7707

Name: AZD4547

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 91.51
Molecular weight 463.26
XLogP 4.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
AZD4547 is being evalauted in clinical trials for various advanced solid tumour types, in combination with other agents, including the anti-PD-L1 immune checkpoint inhibitor durvalumab. Click here to link to a list of these AZD4547 + durvalumab trials at