Ligand id: 7823

Name: AZD6605

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 122.42
Molecular weight 483.11
XLogP 3.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
AZD6605 was developed as a treatment for osteoarthritis based on preclinical studies, including the observation that it inhibited cartilage loss in a guinea pig model of osteoarthritis [1].