Ligand id: 7823

Name: AZD6605

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 122.42
Molecular weight 483.11
XLogP 3.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. De Savi C, Waterson D, Pape A, Lamont S, Hadley E, Mills M, Page KM, Bowyer J, Maciewicz RA. (2013)
Hydantoin based inhibitors of MMP13--discovery of AZD6605.
Bioorg. Med. Chem. Lett., 23 (16): 4705-12. [PMID:23810497]
2. MRC. 
AZD6605 Matrix metallopeptidase 13 (MMP13) inhibitor.
Accessed on 28/10/2014. Modified on 28/10/2014. MRC/AstraZeneca: Mechanisms of Disease Call,