BLZ945

Ligand id: 8250

Name: BLZ945

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 124.61
Molecular weight 398.14
XLogP 2.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Phase 1/2 clinical trial NCT02829723 is evaluating BLZ945 alone or in combination with the anti-PD-1 mAb PDR001 in advanced solid tumours.