dasotraline

Ligand id: 8308

Name: dasotraline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 26.02
Molecular weight 291.06
XLogP 5.48
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Dasotraline is being assessed in Phase III clinical trial as a potential treatment for adults and children with attention-deficit-hyperactivity disorder (ADHD). Click here to link to ClinicalTrials.gov's list of Phase III dasotraline trials.
Mechanism Of Action and Pharmacodynamic Effects
Dasotraline inhibits monoamine reuptake via the serotonin, dopamine and norepinephrine transporters [3].