Ligand id: 8499

Name: elubirixin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 119.15
Molecular weight 462.03
XLogP 2.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
SB-656933 has been evaluated in Phase II clinical trial aiming to reduce neutrophil-mediated airway inflammation in cystic fibrosis patients (NCT00903201 [3]), and in Phase I trials as a potential treatment for chronic obstructive pulmonary disease (COPD).