periciazine

Ligand id: 9216

Name: periciazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 75.8
Molecular weight 365.16
XLogP 3.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved in the UK for the management of schizophrenia or other psychoses, and as short-term adjunctive management of severe anxiety, psychomotor agitation, and violent or dangerously impulsive behaviour.
Mechanism Of Action and Pharmacodynamic Effects
The precise molecular mechanism of action is poorly defined, but is thought in involve antagonism of central dopamine receptors [1] and adrenoceptors [2].
External links