periciazine

Ligand id: 9216

Name: periciazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 75.8
Molecular weight 365.16
XLogP 3.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Kanba S, Suzuki E, Nomura S, Nakaki T, Yagi G, Asai M, Richelson E. (1994)
Affinity of neuroleptics for D1 receptor of human brain striatum.
J Psychiatry Neurosci19 (4): 265-9. [PMID:7918347]
2. Tsukamoto T, Asakura M, Hirata N, Imafuku J, Matsui H, Hasegawa K. (1984)
Interaction of neuroleptics and antidepressants with rat brain alpha 2-receptors: a possible relationship between alpha 2-receptor antagonism and antidepressant action.
Biol. Psychiatry19 (9): 1283-91. [PMID:6149771]