AZD6738

Ligand id: 9390

Name: AZD6738

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 116.23
Molecular weight 412.17
XLogP 2.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
ClinicalTrials.gov has a number of Phase 1 and 2 studies that are ongoing or being planned to evaluate the efficacy of AZD6738 alone or in combination with chemotherapy and/or novel anti-cancer agents. For example Phase 1/2 clinical trial NCT02264678 is evaluating AZD6738 in combination with other drugs, including carboplatin (platinum-based chemotherapy drug), olaparib (PARP inhibitor), and durvalumab (anti-PD-L1 immune checkpoint inhibitor), in a range of advanced solid tumours. Click here to view the entire list of AZD6738 trials on ClinicalTrials.gov.