gemtuzumab ozogamicin

Ligand id: 6775

Name: gemtuzumab ozogamicin

Immunopharmacology Comments
Gemtuzumab ozogamicin is an immune checkpoint modulator that delivers a toxic payload to target cancer cells.
Immunopharmacology Disease
Disease X-Refs Comment References
Acute myeloid leukemia Disease Ontology: DOID:9119
OMIM: 601626
Orphanet: ORPHA519
Approved in particular for CD33-positive AML. However, note that use in this indication has been withdrawn in some jurisdictions due to safety concerns and lack of significant efficacy.