Ligand id: 6891

Name: abatacept

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: abatacept

Immunopharmacology Comments
Abatacept is a selective T cell costimulation modulator used in inflammatory autoimmune diseases, that promotes the coinhibitory activity of the immune checkpoint CTLA-4-CD86/CD80 on T cell activation.
Immunopharmacology Disease
Disease X-Refs Comment References
Psoriatic arthritis Disease Ontology: DOID:9008
Approved drug for PsA.
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Approved drug for RA.
Juvenile idiopathic arthritis- systemic OMIM: 604302
Approved drug for JIA.