roflumilast

Ligand id: 6962

Name: roflumilast

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 60.45
Molecular weight 402.03
XLogP 3.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Disease
Disease X-Refs Comment References
Asthma Disease Ontology: DOID:2841
OMIM: 600807
A phosphodiesterase inhibitor approved to treat asthma.
Chronic obstructive pulmonary disease Disease Ontology: DOID:3083
A phosphodiesterase inhibitor approved to treat COPD.