Ligand id: 9560

Name: AZ3451

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 89.17
Molecular weight 570.13
XLogP 7.4
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Immunopharmacology Comments
Results from studies in animal models suggest that targeting PAR2 may be therapeutically beneficial in rheumatoid arthritis or osteoarthritis.