Ligand id: 9611

Name: ER-27319

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 46.33
Molecular weight 280.16
XLogP 3.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
ER-27319 inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of Fcε receptor I (FcεRI)-mediated activation of Syk [1].