Ligand id: 2561

Name: propafenone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 58.56
Molecular weight 341.2
XLogP 5.52
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Auerbach SS, DrugMatrix® and ToxFX® Coordinator National Toxicology Program. 
National Toxicology Program: Dept of Health and Human Services.
Accessed on 02/05/2014. Modified on 02/05/2014. DrugMatrix,
2. Franqueza L, Valenzuela C, Delp├│n E, Longobardo M, Caballero R, Tamargo J. (1998)
Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels.
Br. J. Pharmacol., 125 (5): 969-78. [PMID:9846634]