Ligand id: 3035

Name: pitavastatin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 90.65
Molecular weight 421.17
XLogP 5.05
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Zhao S, Zhou W, Liu J. (2009)
Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones.
Bioorg. Med. Chem., 17 (23): 7915-23. [PMID:19879766]