Ligand id: 3342

Name: midazolam

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 30.18
Molecular weight 325.08
XLogP 4.95
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Drummond AH, Hughes PJ, Ruiz-Larrea F, Joels LA. (1989)
Use of receptor antagonist in elucidating the mechanism of action of TRH in GH3 cells.
Ann. N. Y. Acad. Sci., 553: 197-204. [PMID:2566295]
2. Waugh DJ, Gaivin RJ, Damron DS, Murray PA, Perez DM. (1999)
Binding, partial agonism, and potentiation of alpha(1)-adrenergic receptor function by benzodiazepines: A potential site of allosteric modulation.
Journal of Pharmacology & Experimental Therapeutics, 291: 1164-1171. [PMID:10565838]