Ligand id: 6576

Name: spiraprilat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 157.54
Molecular weight 438.13
XLogP 4.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Smith EM, Swiss GF, Neustadt BR, McNamara P, Gold EH, Sybertz EJ, Baum T. (1989)
Angiotensin converting enzyme inhibitors: spirapril and related compounds.
J. Med. Chem., 32 (7): 1600-6. [PMID:2544729]