chlorpropamide

Ligand id: 6801

Name: chlorpropamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 83.65
Molecular weight 276.03
XLogP 1.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Ashcroft FM, Gribble FM. (1998)
Correlating structure and function in ATP-sensitive K+ channels.
Trends Neurosci.21 (7): 288-94. [PMID:9683320]
2. Inagaki N, Gonoi T, Clement JP, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J. (1995)
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.
Science270 (5239): 1166-70. [PMID:7502040]
3. Miki T, Nagashima K, Seino S. (1999)
The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells.
J. Mol. Endocrinol.22 (2): 113-23. [PMID:10194514]
4. Rehmann H. (2012)
Epac2: a sulfonylurea receptor?.
Biochem. Soc. Trans.40 (1): 6-10. [PMID:22260657]