Ligand id: 6844

Name: teriflunomide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 73.12
Molecular weight 270.06
XLogP 3.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Heikkil√§ T, Ramsey C, Davies M, Galtier C, Stead AM, Johnson AP, Fishwick CW, Boa AN, McConkey GA. (2007)
Design and synthesis of potent inhibitors of the malaria parasite dihydroorotate dehydrogenase.
J. Med. Chem., 50 (2): 186-91. [PMID:17228860]