Ligand id: 7073

Name: exemestane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 34.14
Molecular weight 296.18
XLogP 3.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Christiansen JS. (1985)
Glomerular hyperfiltration in diabetes mellitus.
Diabet. Med., 2 (4): 235-9. [PMID:2951074]
2. Pagani O, Regan MM, Walley BA, Fleming GF, Colleoni M, L├íng I, Gomez HL, Tondini C, Burstein HJ, Perez EA et al.. (2014)
Adjuvant exemestane with ovarian suppression in premenopausal breast cancer.
N. Engl. J. Med., 371 (2): 107-18. [PMID:24881463]