ulipristal acetate

Ligand id: 7460

Name: ulipristal acetate

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 63.68
Molecular weight 475.27
XLogP 4.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Attardi BJ, Burgenson J, Hild SA, Reel JR. (2004)
In vitro antiprogestational/antiglucocorticoid activity and progestin and glucocorticoid receptor binding of the putative metabolites and synthetic derivatives of CDB-2914, CDB-4124, and mifepristone.
J. Steroid Biochem. Mol. Biol., 88 (3): 277-88. [PMID:15120421]
2. Rewinkel J, Enthoven M, Golstein I, van der Rijst M, Scholten A, van Tilborg M, de Weys D, Wisse J, Hamersma H. (2008)
11-(pyridinylphenyl)steroids--a new class of mixed-profile progesterone agonists/antagonists.
Bioorg. Med. Chem., 16 (6): 2753-63. [PMID:18243712]