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Synonyms: CCL14a | CKβ1 | haemofiltrate CC chemokine 1 (HCC-1) | HCC-1(1-74)
Compound class:
Endogenous peptide in human, mouse or rat
Comment: The ligand is cleaved from the precursor C-C motif chemokine 14 (represents residues 20-93)
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Chou CC, Fine JS, Pugliese-Sivo C, Gonsiorek W, Davies L, Deno G, Petro M, Schwarz M, Zavodny PJ, Hipkin RW. (2002)
Pharmacological characterization of the chemokine receptor, hCCR1 in a stable transfectant and differentiated HL-60 cells: antagonism of hCCR1 activation by MIP-1beta. Br J Pharmacol, 137 (5): 663-75. [PMID:12381680] |
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2. Napier C, Sale H, Mosley M, Rickett G, Dorr P, Mansfield R, Holbrook M. (2005)
Molecular cloning and radioligand binding characterization of the chemokine receptor CCR5 from rhesus macaque and human. Biochem Pharmacol, 71 (1-2): 163-72. [PMID:16298345] |
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3. Richter R, Schulz-Knappe P, John H, Forssmann WG. (2000)
Posttranslationally processed forms of the human chemokine HCC-1. Biochemistry, 39 (35): 10799-805. [PMID:10978165] |
