Ligand id: 7678

Name: AZD8529

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 83.73
Molecular weight 487.18
XLogP 3.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. AstraZeneca. 
AZD8529-Open Innovation.
Accessed on 10/09/2014. Modified on 10/09/2014.,
2. Clayton J etal. (2008)
Oxadiazole Derivatives and Their Use as Metabotropic Glutamate Receptor Potentiators.
Patent number: US20080306077. Assignee: AstraZeneca. Priority date: 04/06/2007. Publication date: 11/12/2008.
3. Cook D, Brown D, Alexander R, March R, Morgan P, Satterthwaite G, Pangalos MN. (2014)
Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework.
Nat Rev Drug Discov, 13 (6): 419-31. [PMID:24833294]