Ligand id: 7820

Name: AZD1386

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 78.51
Molecular weight 423.06
XLogP 4.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. MRC. 
AZD1386 TRPV1 ion channel inhibitor.
Accessed on 28/10/2014. Modified on 28/10/2014. MRC/AstraZeneca: Mechanisms of Disease Call,
2. Quiding H, Jonzon B, Svensson O, Webster L, Reimfelt A, Karin A, Karlsten R, Segerdahl M. (2013)
TRPV1 antagonistic analgesic effect: a randomized study of AZD1386 in pain after third molar extraction.
Pain, 154 (6): 808-12. [PMID:23541425]