Ligand id: 7826

Name: AZD9056

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 61.36
Molecular weight 418.24
XLogP 5.48
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. McInnes IB, Cruwys S, Bowers K, Braddock M. (2014)
Targeting the P2X7 receptor in rheumatoid arthritis: biological rationale for P2X7 antagonism.
Clin. Exp. Rheumatol., 32 (6): 878-82. [PMID:25288220]