Ligand id: 7826

Name: AZD9056

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 61.36
Molecular weight 418.24
XLogP 5.48
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Reached Phase 2 clinical evaluation in RA, but development was discontinued.
Crohn's disease Disease Ontology: DOID:8778
OMIM: 266600
Orphanet: ORPHA206
Developed with potential for treating CD, but development was discontinued.
Chronic obstructive pulmonary disease Disease Ontology: DOID:3083
Developed with potential for treating COPD, but development was discontinued.