Ligand id: 7979

Name: dinutuximab

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Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy.
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Glycobiology of neuroblastoma: impact on tumor behavior, prognosis, and therapeutic strategies.
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Ch14.18 antibody produced in CHO cells in relapsed or refractory Stage 4 neuroblastoma patients: a SIOPEN Phase 1 study.
MAbs, 5 (5): 801-9. [PMID:23924804]
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Method for Treating a GD2 Positive Cancer.
Patent number: US20140170155. Assignee: Apeiron Biologics Ag. Priority date: 18/06/2012. Publication date: 19/06/2014.
5. Mujoo K, Cheresh DA, Yang HM, Reisfeld RA. (1987)
Disialoganglioside GD2 on human neuroblastoma cells: target antigen for monoclonal antibody-mediated cytolysis and suppression of tumor growth.
Cancer Res., 47 (4): 1098-104. [PMID:3100030]
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Analytical characterization of ch14.18: a mouse-human chimeric disialoganglioside-specific therapeutic antibody.
MAbs, 4 (1): 84-100. [PMID:22327432]