example 7 [US8664233]

Ligand id: 8283

Name: example 7 [US8664233]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 78.96
Molecular weight 374.19
XLogP 2.47
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Reichelt C, Schulze A, Daghish M, Ludwig F-A, Heinicke J, Herrmann K, Schuster M, Letschert S, Mugridge K, DeAngelo J. (2014)
Substituted 5H-pyrimido[5,4-B]indoles, method for the production thereof and use thereof for treating non-solid malignant tumors of the blood-producing system.
Patent number: US8664233. Assignee: The Medicines Company (Leipzig) Gmbh. Priority date: 22/12/2006. Publication date: 04/03/2014.